At-home fecal test cuts colon cancer deaths by half in Spanish study

A longitudinal study conducted in Spain tracked 2.2 million adults aged 50 to 69 who participated in a 21-year screening program using a fecal immunochemical test (FIT) every two years. The FIT, which requires no dietary restrictions, laxatives or medical appointments, involves collecting a stool sample at home and mailing it to a laboratory. Results showed a 50 % reduction in colon cancer deaths among participants compared with those who did not undergo the test.

Dr. Alexis Grucela of Northwell Northern Westchester Hospital described the method as simple, non-invasive and affordable, costing under $100 out of pocket. While FITs are more cost-effective and have fewer false positives than other stool tests, they do not replace colonoscopy, which remains necessary for diagnosis and polyp removal. The study underscores the potential public-health benefit of expanding access to FIT screening, especially for individuals unable or unwilling to undergo colonoscopy.