Long-term tadalafil use linked to higher chance of developing glaucoma

A new cohort study published in the British Journal of Ophthalmology examined 73,854 men, comparing 36,927 tadalafil users with an equal number of non-users. Over a five-year period, men on the drug were 22% more likely to develop glaucoma, 32% more likely to experience ocular hypertension, and 33% more likely to start glaucoma treatment. While the research does not prove causation, optometrist Flora Hui noted the correlation and urged pre-treatment and ongoing eye checks, particularly for older patients with family histories of the disease.

Ophthalmologist Andrew White highlighted that blood-pressure fluctuations associated with the medication could exacerbate eye-pressure spikes. The study, based on data from the international TriNetX database, primarily involved white participants, limiting its applicability to other ethnic groups. Australian specialists emphasized that the results should not deter appropriate use of tadalafil for urinary or erectile issues but call for vigilant monitoring of eye health.