Nature issues expression of concern over cancer exosome research paper
Nature has published an editorial expression of concern regarding the 2026 article on tumour exosome integrins and organ-specific metastasis.
The journal flagged the study by Hoshino, Costa-Silva, Shen and colleagues, questioning the validity of its findings on how exosome integrins direct metastasis to particular organs. The notice appears in the official record of the paper, which was originally released in 2026. No further details about the alleged problems were provided in the brief notice. The expression of concern signals that readers should treat the results with caution until the issues are resolved.
Why it matters
It alerts researchers and clinicians that key cancer-metastasis findings may be flawed, affecting future studies and treatments.
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