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Definium Therapeutics reports LSD pill cuts anxiety in Phase 3 trial

Definium Therapeutics announced that its experimental LSD tablet, DT120, significantly reduced symptoms in a Phase 3 study of generalized anxiety disorder.

In a randomized, double-blind trial, 214 participants received either a single dose of DT120, the company’s proprietary LSD formulation, or a placebo. The results showed a marked improvement in anxiety measures for those taking the drug. This follows Definium’s earlier Phase 3 success treating major depression. The company highlighted the statistical significance of the findings.

Why it matters

A new, effective anxiety treatment could expand options for millions suffering from the disorder.

In this story

LSD therapyDT120generalized anxiety disorderPhase 3 trialplaceboclinical studypharmaceutically optimized