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Mouse study suggests puberty may end asthma in some boys

Researchers found that a hormonal shift during puberty can suppress asthma symptoms in male mice, offering clues for why the condition improves in some human boys after puberty.

A new laboratory investigation demonstrated that the surge of sex hormones at puberty reduces airway inflammation in male mice prone to asthma. The findings indicate that similar hormonal changes could explain the observed decline of asthma severity in many adolescent boys. The study highlights a potential biological mechanism linking puberty to respiratory health, though further human research is needed. Results were published in a peer-reviewed scientific journal.

Why it matters

Understanding why asthma often eases after puberty could lead to new treatments for children with the disease.

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asthmapubertymale micesex hormonesairway inflammationimmune responseresearch study
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