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Study Finds Antibiotic Overuse Peaks in Rich Nations While Poor Countries Face Shortages

A new Lancet Public Health analysis shows high-income countries consume the most antibiotics for resistant infections, whereas many low-income nations lack sufficient access.

A recent study in Lancet Public Health challenges the prevailing view that low- and middle-income countries drive antibiotic overuse. Data indicate that high-income nations not only use the greatest volumes of antibiotics for resistant infections but also exceed clinical needs, especially for broad-spectrum "watch" drugs. Conversely, many poorer countries lack adequate supplies, even though they account for more than 80% of the estimated global requirement.

The authors warn that both overuse and underuse fuel resistance, emphasizing the need for precise prescribing and reliable drug availability. They cite the WHO's Access-Watch-Reserve (AWaRe) framework and note the UN General Assembly's 2024 pledge for 70% of use to come from the access group by 2030, a target the study finds broadly met yet unevenly distributed. The analysis urges countries to develop tailored AMR strategies that reflect local disease burdens and resistance patterns.

Why it matters

Understanding where antibiotics are overused or lacking helps shape policies that can curb resistance and save lives worldwide.

In this story

antibiotic overuseantibiotic underuseantimicrobial resistancehigh-income countrieslow-income countriesAWaRe frameworkglobal healthdrug-resistant infections
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