Study warns popular NAD+ supplements may aid cancer growth
New research suggests that NAD+ precursor supplements, promoted by celebrities like Kim Kardashian and Bryan Johnson, could help cancer cells survive and resist chemotherapy.
A recent study from Case Western Reserve University found that oral NAD+ precursors—namely NMN, NR and NAM—can enhance the resilience of pancreatic cancer cells undergoing chemotherapy. By increasing NAD+ levels, the supplements supplied cancer cells with extra energy, lowered oxidative stress, and suppressed the DNA damage pathways that chemotherapy exploits. The investigators observed that tumors became more robust and less susceptible to drug-induced death.
While the supplements are marketed for anti-aging benefits and have been endorsed by figures such as Kim Kardashian and biohacker Bryan Johnson, experts warn they may be dangerous for individuals with active cancer. Dr. Pooja Gidwani emphasizes that the products should not replace lifestyle factors like sleep and exercise, and Jordan Winter calls for routine screening of cancer patients for NAD+ supplement use.
Why it matters
The findings highlight a potential risk of widely used anti-aging supplements for people battling cancer.
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